- Toxicity vs THR benefit
Major autohemotherapy
Literature references
Contact addresses
Therapy I Major autohemotherapy

Hygiene - Set with Micro-Bubble-System Foto
Following the recommendations of the Hygiene Institut of the Gießen University and the internationally published guidelines for the low-dose ozone concept*.

MAH as extracoporeal blood treatment has become the most important form of low risk systemic ozone therapy:
under strict aseptic conditions, 50-100 ml venous blood are withdrawn from the patient into a vacuum flask with sodium citrate as anticoagulant, where the medical ozone/oxygen gas mixture is added to it - extracorporeally in a closed, sterile system - before being re-infused via drip infusion (pressure-free).

The ozone/oxygen mixture passes through the patient's blood evenly, using the micro bubble system to produce a reaction surface as large as possible in the short reaction time (less than 1 second). Thus contact with ozone can take place with nearly all RBC´s and nearly all WBC´s making the ozone reaction as effective as possible, while the oxygen bubbles through, forming a layer of O2 gas above the liquid level in the flask.

Dosage range
Ozone dosage covers a range between 500 µg and max. 4000 µg ozone per treatment, using a quantity of blood between 50 and 100 ml.

Main Indications
Angiopathies, arterial circulatory disturbances,
chronic inflammatory diseases, chronic hepatitis and as a complementary in oncology.

Glucose-6-phosphate-dehydrogenase deficiency
(favism, acute hemolytic anemia)
Hyperthyroidism (if not controlled)
The first 3 months of pregnancy
Major autohemotherapy is not indicated in leukemia

*"Ozone in Medicine: The Low-Dose Ozone Concept - Guidelines and Treatment Strategies"
OS&E 34: 408-424 (2012)